WHEATON® SAFE-GRIND® Potter-Elvehjem Tissue Grinder, Pestle and Tube, 2/Case

• Manufactured from borosilicate glass 3.3
• Exterior plastic coated glass mortar provides greater safety during power homogenization
• PTFE pestle tip with 6.3mm diameter stainless steel rod can be used with power homogenization for soft tissue such as brain or liver
• Components are interchangeable eliminating need to keep parts matched during cleaning
• Unit can be autoclaved / sterilized to prevent cross contamination between samples
• Pestle clearance range: 0.1 – 0.15mm
• Pestle clearance range: 0.1 – 0.15mm

WHEATON® SAFE-GRIND® Potter-Elvehjem Tissue Grinder produce homogenates by a combination of shearing and compression actions. The tissue sample is progressively ground (sheared) into smaller pieces at the rounded end of the pestle as the spinning pestle is lowered into the tube. As the pestle is forced lower into the tube, the sample is displaced and forced between the straight outside wall of the pestle and the inside wall of the tube, compressing the tissue cells until they rupture. When the tube is pulled away from the pestle, a slight vacuum is created that pulls the sample back past the compression area, resulting in an additional homogenization stroke. The degree of homogenization is controlled by the clearance between the pestle’s and tube’s cylindrical section, the rotational speed of the pestle, and the number of compression strokes made. The Potter-Elvehjem tissue grinder has rounded shape on the lower portion of the pestle where th sample is progressively ground smaller. Ground glass pestle versions are suited for connective tissues whereas PTFE pestle versions are used with softer tissues.

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