1,5,6,7-Tetrahydro-4H-indol-4-one, 1 X 5 g (357839-5G)

Iodination of 1,5,6,7-tetrahydro-4H-indol-4-one using 1-chloromethyl­-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetra­fluoroborate) yields α-iodo derivative as the main product. 1,5,6,7-Tetrahydro-4H-indol-4-one may be used in the preparation of: •4-oxo-4,5,6,7-tetrahydro-1H-indole-2-carbonitrile •methyl 2-(4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl)acrylate •3-(4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl)propanenitrile •potent and orally active 5-HT1A agonists, (R)-(+)- and (S)-(-)-1-formyl-6,7,8,9-tetrahydro-N,N-dipropyl-3H-benz[e]indol-8-amines

Read Less