2-(Piperidin-4-yl)benzoic acid hydrochloride, 1 X 100 mg (916854-100MG)

2-(Piperidin-4-yl)benzoic acid hydrochloride is a 4-aryl piperidine useful as a semi-flexible linker in PROTAC development for targeted protein degradation. Incorporation of rigidity into the linker region of bifunctional protein degraders may impact the 3D orientation of the degrader and thus ternary complex formation as well as optimization of drug-like properties. Portal: Building PROTAC® Degraders for Targeted Protein Degradation Crosslinkers for Bioconjugation Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

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