(4-(Bromomethyl)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone, 1 X 100 mg (900598-100MG)

Used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments. Technology Spotlight: Trifuctional Probe Building Blocks Development of Sulfonamide Photoaffinity Inhibitors for Probing Cellular γ-Secretase A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS

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