6,6′-Dithiodinicotinic acid, 1 X 5 g (373605-5G)

6,6′-Dithiodinicotinic acid is reported as sulphydryl reagent. 6,6′-Dithiodinicotinic acid is reported to react with thiols, to afford a disulfide and 6-mercaptonicotinic acid. Interaction of 6,6′-dithiodinicotinic acid with the homogenates of Ehrlich ascites cells has been reported. 6,6′-Dithiodinicotinic acid may be employed as: •specific thiol blocker to investigate the radioprotective effect of mercaptoethylamine on the thiol level of the outer cell membrane of the Ehrlich ascites tumor cells •modifier to investigate the polar microenvironment around the reactive Cys283 of rabbit muscle creatine kinase •dipyridyl-dithio substrate to evaluate the protein disulfide-thiol interchange activity of the auxin stimulated NADH: protein disulfide reductase (NADH oxidase) of soybean plasma membranes •water-soluble reagent in a study for introducing, in buffered saline, a reactive sulfhydryl group on water-soluble molecules bearing an alkyl-amino group •chromogen for sulfhydryl groups in the Ellman method for cholinesterase determinations •spectrophotometric determination of thiols and of total glutathione in human blood

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