Anti-Cathepsin D (Ab-1) Mouse mAb (BC011), 100 µG (IM03-100UG)

Anti-Cathepsin D (Ab-1), mouse monoclonal, clone BC011, recognizes latent and mature form and the ~34 kDa subunit in breast carcinoma tissue extracts. It is validated for WB and for paraffin sections. Immunoblotting (1 µg/ml) Paraffin Sections (5 µg/ml, trypsin pre-treatment required) Does not detect the ~14 kDa subunit of cathespin D, nor will it detect cathespins B or L. Cathepsins are secreted and accumulate in conditioned tissue culture media and can be detected by immunoblotting from this source. Some cell extracts do not contain sufficient cathepsin for detection by immunoblotting. Antibody should be titrated for optimal results in individual systems. mature, human cathepsin D Toxicity: Standard Handling (A)

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