Anti-coronavirus (SARS-CoV-2) spike S1, mouse, mAb

Anti-coronavirus spike S1, mouse, monoclonal antibody. Its genome encodes four structural proteins, i.e. spike (S), envelope (E), membrane (M), and nucleocapsid (N). The spike protein (S-protein) contains two subunits, S1 and S2. S1 defines the range of the hosts and specificity of the virus, thus recognizes and binds with the cell surface receptor. S2 subunit contains basic elements needed for the membrane fusion. The spike protein is the common target for neutralizing antibodies and vaccines. Synthetic peptide corresponding to Spike S1 subunit aa 295-313 was used as immunogen to produce this monoclonal antibody.

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