Carbonic Anhydrase 1 (CA1) Rabbit mAb, Monoclonal (A4406) | ABclonal Technology™

ABclonal Technology™ Carbonic Anhydrase 1 (CA1) Rabbit mAb (A4406) is a monoclonal antibody raised in rabbit against CA1. It is validated for WB and ELISA. Confirmed reactivity includes Mouse and Rat. The antibody has an IgG isotype and an observed molecular weight of 29kDa. It is affinity purified.

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This CA1 gene is closely linked to the CA2 and CA3 genes on chromosome 8. It encodes a cytosolic protein that is found at the highest level in erythrocytes. Allelic variants of this gene have been described in some populations. Alternative splicing and the use of alternative promoters results in multiple transcript variants.

• Host Species: Rabbit
• Isotype: IgG
• Species Reactivity: Mouse, Rat
• Validated Applications: WB, ELISA
• Recommended Dilution: WB,1:500 - 1:1000; ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
• Purity: Affinity purification
• Observed MW: 29kDa
• UniProt ID: P00915
• Storage: Store at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

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