Carbonic Anhydrase 9 (CA9/G250) Rabbit mAb, Monoclonal (A4934) | ABclonal Technology™

ABclonal Technology™ Carbonic Anhydrase 9 (CA9/G250) Rabbit mAb (A4934) is a monoclonal antibody raised in rabbit against CA9. It is validated for WB, IHC-P and ELISA. Confirmed reactivity includes Human. The antibody has an IgG isotype and an observed molecular weight of 30-60kDa. It is affinity purified.

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.

• Host Species: Rabbit
• Isotype: IgG
• Species Reactivity: Human
• Validated Applications: WB, IHC-P, ELISA
• Recommended Dilution: WB,1:500 - 1:2000; IHC-P,1:50 - 1:200; ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
• Purity: Affinity purification
• Observed MW: 30-60kDa
• UniProt ID: Q16790
• Storage: Store at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

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