Casein Kinase 1δ (aa 1-294) Protein, active, 10 µg, 1 X 250 µG (14-520M)

Research area: Cell signaling Research Category: Metabolism Research Subcategory: Obesity Protein Target: CK1γδ Target Sub-Family: CK1 Casein Kinase 1δ (CK1δ ) is a serine/threonine kinase that belong to the family of casein kinase 1. The protein structure consists of anti-parallel β-sheet strands at N-terminal lobe (N-lobe) and α-helices and loop structures at the larger C-terminal lobe (C-lobe). Research Category Metabolism Glutathione-agarose For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. Casein Kinase 1δ (CK1δ) is implicated in multiple cellular processes, including membrane trafficking, cytokinesis, circadian rhythm, and tumorigenesis. It interacts with critical molecules within cancer-related signaling pathways, such as Wnt/β-catenin, PI3K/AKT, and Hedgehog. Therefore, mutations or overexpression of the CK1δ coding gene can potentially contribute to the onset and progression of cancer. 6 months at -20°C routinely evaluated by phosphorylation of KRRRALS(p)VASLPGL

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