CryoShield Platinum™ Serum-Free Cryopreservation Medium (Chemically Defined) for Sensitive Cells and Tissues, DSMO-Free, Sterile-Filtered, 100mL

CryoShield Platinum™ by CellPro is a chemically defined, DMSO-free cryopreservation medium engineered to support high post-thaw viability and functionality without the cytotoxicity commonly associated with dimethyl sulfoxide (DMSO). This serum-free, protein-free, and animal-origin–free formulation is ideal for preserving sensitive cells and tissues including NK-T cells, CAR-T cells, macrophages, iPSCs, ESCs, organoids, and epithelial models.

Developed for use in long-term storage at –80°C without liquid nitrogen, CryoShield Platinum™ delivers superior performance compared to conventional DMSO-containing and DMSO-free alternatives. It fully protects cellular components—including membranes, mitochondria, and nuclei—while minimizing apoptosis, necrosis, and structural damage caused by freezing and thawing.

Key Features

• 100% DMSO-free, eliminating DMSO-related cytotoxicity
• Serum-free, protein-free, and animal-origin–free
• Chemically defined and GMP-grade
• Supports long-term cryostorage at –80°C without LN₂
• No antibiotics or additives required
• Maintains high cell viability and functionality post-thaw
• Validated in human PBMC-derived NK-T cells, hepatocytes, and HEK293T cells
• Outperforms Cryostor CS10, CryoSofree, and Stem Cellbanker (DMSO-Free)

Validated Cell Types

• NK-T cells, CAR-T cells, macrophages
• Cord blood, bone marrow, hepatocytes
• Epithelial, immune, fat-derived, and dental stem cells
• iPSCs, ESCs, fibroblasts, neuron cells
• Cell lines including CHO, HEK293T, Hela, MCF-7, and more

Performance Data Highlights

• 90% viability in NK-T and primary hepatocytes
• Lower apoptosis and higher live cell counts compared to Cryostor CS10
• Enhanced plating efficiency and morphology retention in HEK293T after 7-day storage
• Peak recovery without the need for DMSO or serum additives

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