Cytochrome P450 2E1 (CYP2E1) Rabbit mAb, Monoclonal (A23030) | ABclonal Technology™

ABclonal Technology™ Cytochrome P450 2E1 (CYP2E1) Rabbit mAb (A23030) is a monoclonal antibody raised in rabbit against CYP2E1. It is validated for WB, IF-P, IHC-P and ELISA. Confirmed reactivity includes Human, Mouse and Rat. The antibody has an IgG isotype and an observed molecular weight of 50-57kDa. It is affinity purified.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.

• Host Species: Rabbit
• Isotype: IgG
• Species Reactivity: Human, Mouse, Rat
• Validated Applications: WB, IF-P, IHC-P, ELISA
• Recommended Dilution: WB,1:5000 - 1:50000; IF-P,1:200 - 1:2000; IHC-P,1:4000 - 1:16000; ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
• Purity: Affinity purification
• Observed MW: 50-57kDa
• UniProt ID: P05181
• Storage: Store at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

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