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Dextran 70 is a high-molecular-weight polysaccharide composed of glucose units linked primarily by α-1,6-glycosidic bonds, with occasional α-1,3 branches. It appears as a white to off-white powder and is highly soluble in water, forming viscous solutions. Dextran 70 is widely used in biomedical and laboratory applications, including as a plasma volume expander, a stabilizer in protein formulations, and a component in density gradient media for cell separation.
In research and laboratory settings, Dextran 70 is commonly employed for isolating cells or organelles via centrifugation, enhancing osmotic balance in cell culture, and as a crowding agent in biochemical assays. Its high molecular weight and biocompatibility make it useful in applications that require viscosity modulation, cell protection, or controlled molecular interactions.
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