Digitonin, Water Soluble

Digitonin, Water Soluble, is a steroidal saponin derived from the plant Dioscorea species, known for its ability to selectively permeabilize cellular membranes by interacting with cholesterol. Its water-soluble form allows convenient preparation of aqueous solutions, making it highly useful in laboratory applications for gentle cell lysis, membrane protein extraction, and studies of organelle integrity without complete disruption of cellular structures.

This reagent is commonly employed in biochemical and cell biology research to isolate mitochondria, study membrane-bound proteins, or perform selective permeabilization in functional assays. Its water solubility and mild action make it a preferred choice when maintaining the native state of proteins or organelles is critical. Standard laboratory safety procedures should be followed when handling Digitonin, as it is bioactive and can cause irritation.

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