Erythromycin, 1 X 5 g (E5389-5G)

Chemical structure: macrolide Erythromycin has been used: •as a supplement for nutrient broth medium for culturing green fluorescent protein (GFP)- expressing E. coli •as a model drug to determine small intestinal (SMI) microtissue viability using the MTT assay{254 •as an antibiotic to study the treatment strategies of chronic infections Mode of Action: Erythromycin acts by inhibiting elongation at the transpeptidation step, specifically aminoacyl translocation from the A-site to P-site by binding to the 50s subunit of the bacterial 70s rRNA complex. Antimicrobial Spectrum: This product acts against both gram-negative and gram-positive bacteria. This product is soluble in water at 2 mg/mL, with a 0.067% solution in water yielding a pH of 8.0-10.5. It is also soluble in ethanol at 50 mg/mL, yielding a clear, colorless to faint yellow solution. It is freely soluble in alcohol, acetone, chloroform, acetonitrile and ethyl acetate but forms salts with acids. All solutions should be protected from light. This product is stable in solution at 37°C for 3 days. Stock solutions should be stored at 2-8°C.

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