Fibronectin, Bovine Plasma, 1 X 1 mg (341631-1MG)

Fibronectin is an extracellular matrix (ECM) glycoprotein. It is expressed in various cell types. Fibronectin exists as a dimer and is made up of identical subunits which are linked covalently via a disulfide bond at their C-termini. Fibronectin, Bovine Plasma has been used as an extracellular matrix (ECM) substrate to coat dishes or polyacrylamide hydrogels for adhering: •human melanoma cancer cells •human breast epithelial cells •mouse embryonic fibroblasts In 150 mM NaCl, 20 mM sodium phosphate buffer, pH 7.3. Fibronectin plays a role in cell adhesion, growth, migration, and differentiation. It binds to several molecules such as integrins, heparin, fibrin, and collagen. single band by SDS-PAGE Following initial thaw, aliquot and freeze (-20°C). Toxicity: Standard Handling (A)

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