FK-506 [Tacrolimus] [Fujimycin]

FK-506, also known as tacrolimus or fujimycin, is a macrolide compound that functions as a potent immunosuppressant by inhibiting calcineurin, a phosphatase involved in T-cell activation. It binds to FK-binding proteins (FKBPs), forming a complex that blocks downstream signaling pathways required for immune response activation.

In laboratory and biochemical research, FK-506 is commonly used in studies of T-cell signaling, immunoregulation, calcineurin inhibition, and protein-protein interactions involving FKBP complexes. It is also utilized in investigations of signal transduction pathways and cellular responses to immunosuppressive agents. Its high-purity form ensures reproducible and reliable results in experimental protocols.

This product is intended for laboratory research use only and is not for diagnostic or therapeutic applications.

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