Glutaminase (GLS) Rabbit mAb, Monoclonal (A23189) | ABclonal Technology™

ABclonal Technology™ Glutaminase (GLS) Rabbit mAb (A23189) is a monoclonal antibody raised in rabbit against GLS. It is validated for WB, IF/ICC, IF-P and ELISA. Confirmed reactivity includes Human, Mouse and Rat. The antibody has an IgG isotype and an observed molecular weight of 55-65 kDa. It is affinity purified.

This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants.

• Host Species: Rabbit
• Isotype: IgG
• Species Reactivity: Human, Mouse, Rat
• Validated Applications: WB, IF/ICC, IF-P, ELISA
• Recommended Dilution: WB,1:1000 - 1:5000; IF/ICC,1:50 - 1:200; IF-P,1:50 - 1:200; ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
• Purity: Affinity purification
• Observed MW: 55-65 kDa
• UniProt ID: O94925
• Storage: Store at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Read Less