Integrin alpha V (ITGAV/CD51) Rabbit pAb, Polyclonal (A2091) | ABclonal Technology™

ABclonal Technology™ Integrin alpha V (ITGAV/CD51) Rabbit pAb (A2091) is a polyclonal antibody raised in rabbit against ITGAV. It is validated for WB, IHC-P, IP and ELISA. Confirmed reactivity includes Human, Mouse and Rat. The antibody has an IgG isotype and an observed molecular weight of 130kDa. It is affinity purified.

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

• Host Species: Rabbit
• Isotype: IgG
• Species Reactivity: Human, Mouse, Rat
• Validated Applications: WB, IHC-P, IP, ELISA
• Recommended Dilution: WB,1:1000 - 1:5000; IHC-P,1:50 - 1:200; IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells; ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
• Purity: Affinity purification
• Observed MW: 130kDa
• UniProt ID: P06756
• Storage: Store at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.

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