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n-Dodecyl-β-D-Maltoside (DDM) is a nonionic detergent supplied as a white to off-white crystalline powder. It is widely used in biochemical and molecular biology research for solubilizing membrane proteins while maintaining their native structure and activity.
In laboratory applications, DDM is commonly used for membrane protein extraction, stabilization, and purification, as well as for crystallography, enzymatic assays, and studies of protein-lipid interactions. Its mild, non-denaturing properties help preserve protein functionality and structural integrity during solubilization and downstream biochemical analyses.
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