N,N′-Disuccinimidyl carbonate, 1 X 5 g (43720-5G)

N,N′-Disuccinimidyl carbonate (DSC) can be used to synthesize: • Various carbamate derivatives from primary and sterically hindered secondary alcohols by alkoxycarbonylation. • Active carbonate resins from 4-hydroxymethylpolystyrene and 4-hydroxymethyl-3-nitrobenzamido resins via hydroxy functional groups. • Aza-glycinyl dipeptides, important intermediates for the preparation of various azapeptides. It may be also used: •In the two-step preparation of 5-(6-(azidomethyl)nicotinamido)pentanoic acid, a copper-chelating picolyl azide derivative. •To activate the hydroxyl group of the hapten, γ-hydroxyphenylbutazone (HPBZ) so that HPBZ can effectively bind with human serum albumin(HSA)-immunogen to form a hapten-protein conjugate. Convenient reagent for preparing N-succinimidyl esters of N-protected amino acids and other acids; activated carbonate, e.g. synthesis of ureas and carbamates; coupling of ligands to proteins (via lysines).

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