P-Selectin, Human, Recombinant, CHO Cells, 50 µG (561306-50UG)

Recombinant, human P-selectin consisting of 730 amino acids minus the transmembrane and cytoplasmic domains expressed in CHO cells. This glycoprotein is expressed on activated platelets and endothelial cells. A specific interaction between P-selectin and P-selectin glycoprotein ligand-1, present on numerous cell types, promotes adhesion and acts along with L-selectin in establishing an initial interaction between circulating leukocytes and the endothelium. Lyophilized from Dulbecco’s D-PBS (containing calcium and magnesium), 1% sorbitol. Shown to bind to P-selectin ligands on U937 cells. Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C. Toxicity: Standard Handling (A)

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