Recombinant Human HGF receptor/c-MET/MET Protein (RP01041) | ABclonal Technology™

ABclonal Technology™ Recombinant Human HGF receptor/c-MET/MET Protein (RP01041) is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu25-Thr932) of human HGF R/c-MET (Accession #NP_000236.2) fused with a 6×His tag at the C-terminus. Purity: ≥ 95 % as determined by SDS-PAGE. Each lot is quality controlled to support reproducible results in research applications.

Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a glycosylated receptor tyrosine kinase (RTK) that has been shown to be overexpressed and/or mutated in a variety of malignancies. Normal HGF/HGFR signaling is essential for embryonic development, tissue repair or wound healing, whereas aberrantly active HGFR has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes. HGFR protein is a multifaceted regulator of growth, motility, and invasion, and is normally expressed by cells of epithelial origin.

• Species: Human
• Expression System: HEK293 cells
• Tag: C-His
• Purity: ≥ 95 % as determined by SDS-PAGE.
• Endotoxin: < 0.1 EU/μg of the protein by LAL method.
• Bioactivity: Measured by its binding ability in a functional ELISA. Immobilized recombinant human HGFR at 2 μg/mL (100 μL/well) can bind Rrecombinant human HGF with a linear range of 25-250 ng/mL.
• UniProt ID: P08581
• Formulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
• Storage: Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.; After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.

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