Recombinant Human TNFSF10/TRAIL/CD253 Protein (RP01541) | ABclonal Technology™

ABclonal Technology™ Recombinant Human TNFSF10/TRAIL/CD253 Protein (RP01541) is produced by E. coli expression system. The target protein is expressed with sequence (Val114-Gly281) of human TNFSF10/TRAIL/CD253 (Accession #NP_003801.1) fused with no additional amino acid. It is supplied untagged. Purity: ≥ 95 % as determined by SDS-PAGE.

Tumor necrosis factor ligand superfamily member 10 (TNFSF10), also known as TNF-related apoptosis-inducing ligand (TRAIL), Apo-2 ligand, and CD253, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. TNFSF10 / Apo-2L / CD253 functions as a ligand that induces the process of cell death called apoptosis. TNFSF10 / TRAIL shows homology to other members of the tumor necrosis factor superfamily. As one member of the cluster of differentiation system, TNFSF10 / CD253 is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified.

• Species: Human
• Expression System: E. coli
• Tag: No tag
• Purity: ≥ 95 % as determined by SDS-PAGE.
• Endotoxin: < 0.1 EU/μg of the protein by LAL method.
• Bioactivity: Immobilized Human TNFSF10 Protein at 5 μg/mL (100 μL/well) can bind HumanTNFRSF11B with a linear range of 0.0012-107.86 ng/mL.
• UniProt ID: P50591
• Formulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
• Storage: Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.; After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.

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