α-Synuclein, Human, Recombinant, E. coli, 200 µG (575001-200UG)

Research area: Neuroscience Recombinant, human α-synuclein expressed in E. coli. α-Synuclein is an acidic neuronal protein of 140 amino acids (amino acid residues 1 -140). α-Synuclein, Human, Recombinant, E. coli has been used to enhance the filter trap assay for identification of aggregated alpha-synuclein in brain samples. In 100 mM NaCl, 20 mM Tris-HCl, 1 mM MgCl₂, pH 7.5. Kahle, P.J, et al. 2001. Am. J. Pathol.159, 2215. Kim, J. 1997. Mol. Cells7, 78. Paik, S.R. 1997. Arch. Biochem. Biophys.344, 325. Jakes, R., et al. 1994. FEBS Lett.345, 27. Ueda, K., et al. 1993. Proc. Natl. Acad. Sci. USA90, 11282. α-Synuclein been implicated in the pathogenesis of Parkinson’s disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells. Following initial thaw, aliquot and freeze (-20°C). Toxicity: Standard Handling (A)

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