Ubiquitin Rabbit mAb, Monoclonal (A23483) | ABclonal Technology™

ABclonal Technology™ Ubiquitin Rabbit mAb (A23483) is a monoclonal antibody raised in rabbit against UBB. It is validated for WB, IHC-P, IF/ICC and ELISA. Confirmed reactivity includes Human and Mouse. The antibody has an IgG isotype and an observed molecular weight of 10 kDa or above. It is affinity purified.

This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants.

• Host Species: Rabbit
• Isotype: IgG
• Species Reactivity: Human, Mouse
• Validated Applications: WB, IHC-P, IF/ICC, ELISA
• Recommended Dilution: WB,1:500 - 1:2000; IHC-P,1:50 - 1:200; IF/ICC,1:50 - 1:200; ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
• Purity: Affinity purification
• Observed MW: 10 kDa or above
• UniProt ID: P0CG47
• Storage: Store at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

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